Search on: 2-OXOISOVALERATE DEHYDROGENASE (ACYLATING) 
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Descriptor English:   2-Oxoisovalerate Dehydrogenase (Acylating) 
Descriptor Spanish:   2-Oxoisovalerato Deshidrogenasa (Acilante) 
Descriptor Portuguese:   2-Oxoisovalerato Desidrogenase (Acilante) 
Tree Number:   D08.811.682.657.350.825
Definition English:   An NAD+ dependent enzyme that catalyzes the oxidation 3-methyl-2-oxobutanoate to 2-methylpropanoyl-CoA. It plays a role in the degradation of VALINE; LEUCINE; and ISOLEUCINE. 
History Note English:   2006(1980); use AMINO ACIDS, BRANCHED-CHAIN 1979, & KETO ACIDS & VALERATES 1973-1979 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   50621 
Unique Identifier:   D050645 

Occurrence in VHL:
 

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